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| DC Field | Value | Language |
|---|---|---|
| dc.creator | Soriano, Francisco | - |
| dc.creator | Rodríguez-Cerrato, Violeta | - |
| dc.creator | García, Pedro | - |
| dc.creator | Huelves, Lorena | - |
| dc.creator | García, Ernesto | - |
| dc.creator | Prado, Gema del | - |
| dc.creator | Gracia, Matilde | - |
| dc.creator | Ponte, Carmen | - |
| dc.creator | López, Rubens | - |
| dc.date | 2008-02-06T12:32:45Z | - |
| dc.date | 2008-02-06T12:32:45Z | - |
| dc.date | 2007-06-18 | - |
| dc.date.accessioned | 2017-01-31T00:59:58Z | - |
| dc.date.available | 2017-01-31T00:59:58Z | - |
| dc.identifier | Antimicrob Agents Chemother. 2007 September; 51(9): 3371–3373 | - |
| dc.identifier | PMCID: 2043201 | - |
| dc.identifier | 0066-4804 | - |
| dc.identifier | http://hdl.handle.net/10261/2875 | - |
| dc.identifier | 10.1128/AAC.00137-07 | - |
| dc.identifier.uri | http://dspace.mediu.edu.my:8181/xmlui/handle/10261/2875 | - |
| dc.description | The in vitro and in vivo antipneumococcal activities of the main pneumococcal autolysin (LytA) and Cpl-1, a lysozyme encoded by phage Cp-1, were studied. Intraperitoneal therapy with LytA or high-dose Cpl-1 remarkably reduced peritoneal bacterial counts (>5 log10 CFU/ml) compared with those for the controls. After intravenous injection, LytA was the most effective treatment. | - |
| dc.description | This research was supported by grants from the Red Tematica de Investigacion Cooperativa Spanish Pneumococcal Infection Study Network (grant G03/103) (Ministerio de Sanidad y Consumo, Spain) and the program COMBACT Nuevas Dianas para Combatir a las Bacterias Patogenas (grant S-BIO-026-2006) (Consejerıa de Educacion, Comunidad de Madrid, Madrid, Spain). L.H. and G.D.P. received scholarships from the Fundacio´n Conchita Ra´bago; M.G. received a scholarship from the Fondo de Investigaciones Sanitarias, Ministerio de Sanidad y Consumo, Spain. | - |
| dc.description | Peer reviewed | - |
| dc.format | 71359 bytes | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | American Society for Microbiology | - |
| dc.rights | closedAccess | - |
| dc.title | Pneumococcal LytA Autolysin, a Potent Therapeutic Agent in Experimental Peritonitis-Sepsis Caused by Highly β-Lactam-Resistant Streptococcus pneumoniae | - |
| dc.type | Artículo | - |
| Appears in Collections: | Digital Csic | |
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