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http://dspace.mediu.edu.my:8181/xmlui/handle/10261/4097Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Cortés-Ledesma, Felipe | - |
| dc.creator | Piccoli, Giaccomo de | - |
| dc.creator | Haber, James E. | - |
| dc.creator | Aragón, Luis | - |
| dc.creator | Aguilera, Andrés | - |
| dc.date | 2008-05-08T16:09:12Z | - |
| dc.date | 2008-05-08T16:09:12Z | - |
| dc.date | 2007-04-15 | - |
| dc.date.accessioned | 2017-01-31T01:12:39Z | - |
| dc.date.available | 2017-01-31T01:12:39Z | - |
| dc.identifier | Cell Cycle 6(8): 914-918 (2007) | - |
| dc.identifier | 1538-4101 (Print) | - |
| dc.identifier | 1551-4005 (Online) | - |
| dc.identifier | http://hdl.handle.net/10261/4097 | - |
| dc.identifier | 10.4161/cc.6.8.4107 | - |
| dc.identifier.uri | http://dspace.mediu.edu.my:8181/xmlui/handle/10261/4097 | - |
| dc.description | PMID: 17404505.-- Previously published online as a Cell Cycle E-publication: http://www.landesbioscience.com/journals/cc/abstract.php?id=4107 | - |
| dc.description | Homologous recombination (HR) is one of the key mechanisms responsible for the repair of DNA double-strand breaks (DSBs), including those that occur during DNA replication. Recent studies in yeast and mammals have uncovered that the SMC complexes cohesins and Smc5-Smc6 are recruited to induced DSBs, and play a role in the maintenance of genome stability by favouring SCR as the main recombinational DSB repair mechanism. These new results raise intriguing questions such as whether SMC proteins might play a functional role at collapsed replication forks, which may represent the main source of spontaneous recombinogenic damage. A deeper knowledge of the role of SMC proteins in DSB repair should contribute to a better understanding of chromosome dynamics and stability. | - |
| dc.description | Peer reviewed | - |
| dc.format | 21663 bytes | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Landes Bioscience | - |
| dc.relation | http://dx.doi.org/10.4161/cc.6.8.4107 | - |
| dc.rights | openAccess | - |
| dc.subject | Sister chromatid exchange | - |
| dc.subject | Double-strand break repair | - |
| dc.subject | Homologous Recombination | - |
| dc.subject | Break-induced replication | - |
| dc.subject | Collapsed replication forks | - |
| dc.subject | Cohesins | - |
| dc.subject | MRX/MRN complex | - |
| dc.subject | Smc5-Smc6 | - |
| dc.subject | SMC complexes | - |
| dc.title | SMC proteins, new players in the maintenance of genomic stability | - |
| dc.type | Artículo | - |
| Appears in Collections: | Digital Csic | |
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