Discovery of Inhibitors of Protein-Protein Interactions from Combinatorial Libraries

Please use this identifier to cite or link to this item: http://dspace.mediu.edu.my:8181/xmlui/handle/10261/4336

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DC Field	Value	Language
dc.creator	Vicent, María J.	-
dc.creator	Pérez-Payá, Enrique	-
dc.creator	Orzáez, Mar	-
dc.date	2008-05-19T10:10:17Z	-
dc.date	2008-05-19T10:10:17Z	-
dc.date	2007-01	-
dc.date.accessioned	2017-01-31T01:22:01Z	-
dc.date.available	2017-01-31T01:22:01Z	-
dc.identifier	Curr Top Med Chem 7 (1): 83-95	-
dc.identifier	http://hdl.handle.net/10261/4336	-
dc.identifier.uri	http://dspace.mediu.edu.my:8181/xmlui/handle/10261/4336	-
dc.description	The definitive version is available at http://www.bentham.org/ctmc/index.htm	-
dc.description	Protein-protein interactions play a central role within numerous processes in the cell. The relevance of the processes in which this type of interactions are implicated make them responsible for many pathological situations. In the last decade protein-protein interfaces have shown their potential as new drug targets, and combinatorial chemistry has been defined as a useful tool in this line. This review gives a global vision of the actual situation of combinatorial chemistry, highlighting its applicability to high-throughput drug discovery and giving some crucial examples of its contribution to find modulators of protein-protein interactions	-
dc.description	Peer reviewed	-
dc.format	118239 bytes	-
dc.format	application/pdf	-
dc.language	eng	-
dc.publisher	Bentham Science Publishers	-
dc.rights	openAccess	-
dc.title	Discovery of Inhibitors of Protein-Protein Interactions from Combinatorial Libraries	-
dc.type	Artículo	-
Appears in Collections:	Digital Csic

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