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DC Field | Value | Language |
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dc.creator | Pandey M | - |
dc.creator | Thomas S | - |
dc.creator | Mathew A | - |
dc.creator | Nair M | - |
dc.date | 2003 | - |
dc.date.accessioned | 2013-05-30T11:10:13Z | - |
dc.date.available | 2013-05-30T11:10:13Z | - |
dc.date.issued | 2013-05-30 | - |
dc.identifier | http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2003;volume=49;issue=1;spage=25;epage=8;aulast=Pandey | - |
dc.identifier | http://www.doaj.org/doaj?func=openurl&genre=article&issn=00223859&date=2003&volume=49&issue=1&spage=25 | - |
dc.identifier.uri | http://koha.mediu.edu.my:8181/jspui/handle/123456789/4404 | - |
dc.description | BACKGROUND: Malignant tumours of the minor salivary glands are rare and constitute less than 0.5% of all malignant neoplasms. AIM: This study was carried out to evaluate the clinical presentation, site distribution, treatment, survival and predictors of survival in malignant minor salivary gland tumours. SETTING: A tertiary care, superspeciality referral hospital. DESIGN: Retrospective analysis. PATIENTS AND METHOD: Forty-two cases of minor salivary gland tumours treated over a period of 17 years were reviewed for clinical presentation, histopathology, stage distribution, treatment and treatment outcome. STATISTICAL ANALYSIS: Survival by Kaplan Meier Method and the outcomes were compared using log-rank test. RESULTS: The mean age of the patients was 46.9 years with a male to female ratio of 1.4:1. Majority of the patients presented with a painless progressive swelling, with 13 (31%) of them in T2 stage. About one-third of the patients had palpable lymph nodes at presentation, while none had distant metastasis. Palate was the commonest site and mucoepidermoid carcinoma was the commonest hispathological type. About 1/3 of the patients were treated with primary surgery and were followed up by adjuvant radiotherapy. Seven patients underwent palliative treatment alone. Over a mean follow-up of 30 months, 5 patients failed. The disease free survival was 72% at 5-year, none of the factors studied were found to significantly influence survival. CONCLUSIONS: Results of the present study suggest that minor salivary gland tumours should be treated with primary surgery irrespective of site and histological type to achieve best loco-regional control and survival. | - |
dc.publisher | Medknow Publications | - |
dc.source | Journal of Postgraduate Medicine | - |
dc.subject | Adolescent | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Carcinoma | - |
dc.subject | diagnosis | - |
dc.subject | pathology | - |
dc.subject | therapy | - |
dc.subject | Disease-Free Survival | - |
dc.subject | Female | - |
dc.subject | Human | - |
dc.subject | Male | - |
dc.subject | Middle Age | - |
dc.subject | Neoplasm Staging | - |
dc.subject | Palate | - |
dc.subject | pathology | - |
dc.subject | Retrospective Studies | - |
dc.subject | Salivary Gland Neoplasms | - |
dc.subject | diagnosis | - |
dc.subject | pathology | - |
dc.subject | therapy | - |
dc.subject | Survival Analysis | - |
dc.subject | Treatment Outcome | - |
dc.title | Malignant tumours of the minor salivary glands: a survival analysis of 17 years from a tertiary referral cancer centre. | - |
Appears in Collections: | Health Sciences |
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