Please use this identifier to cite or link to this item: http://dspace.mediu.edu.my:8181/xmlui/handle/123456789/4428
Title: Cutaneous leishmaniasis: an overview.
Keywords: Animal
Antimony Sodium Gluconate
therapeutic use
Antiprotozoal Agents
therapeutic use
Cryotherapy
Human
Leishmania
classification
Leishmaniasis
Cutaneous
diagnosis
epidemiology
pathology
therapy
Meglumine
therapeutic use
Organometallic Compounds
therapeutic use
Issue Date: 30-May-2013
Publisher: Medknow Publications
Description: Leishmaniasis is a major world health problem, which is increasing in incidence. In Northern Europe it is seen in travellers returning from endemic areas. The protozoa is transmitted by sandflies and may produce a variety of clinical syndromes varying from a simple ulcer to fatal systemic disease. This review considers the management of simple cutaneous leishmaniasis. Patients usually have a single ulcer that may heal spontaneously, requiring only topical, or no treatment at all. Lesions caused by Leishmania braziliensis may evolve into the mucocutaneous form, ′espundia′, and should be treated with systemic antimony. Sodium stibogluconate 20mg/kg/day i.v. for 20 days is the appropriate first line treatment in these cases. Although it may cause transient bone marrow suppression, liver damage, a chemical pancreatitis, and disturbances in the electrocardiogram, it appears safe. The success of treatment should be assessed 6 weeks after it has been completed and patients should be followed up for 6 months.
URI: http://koha.mediu.edu.my:8181/jspui/handle/123456789/4428
Other Identifiers: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2003;volume=49;issue=1;spage=50;epage=4;aulast=Hepburn
http://www.doaj.org/doaj?func=openurl&genre=article&issn=00223859&date=2003&volume=49&issue=1&spage=50
Appears in Collections:Health Sciences

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