Please use this identifier to cite or link to this item: http://dspace.mediu.edu.my:8181/xmlui/handle/123456789/4717
Title: Khorasan Disease: Prevalence of HTLV-I Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) In West Azarbaijan from 2004 to 2007
Keywords: HTLV-I
HAM/TSP
Spastic paraparesis
Iran
Issue Date: 30-May-2013
Publisher: Iranian Hospital, Dubai
Description: Background: Because of the low prevalence of Human T Lymphotropic Virus type I (HTLV-I) in comparison withKhorasan Province, considering HTLV-I as an etiology of spastic paraparesia, it may be neglected in evaluationof spastic paraparesis in the other regions of Iran. Some reports of spastic paraparetic patients due to HTLV-Iinfection in West Azarbaijan, caused us to reconsider the importance of HTLV-I epidemiology in the other areasof the country.Methods: All spastic paraparetic patients who referred to Motahari and Imam Khomeini educational hospitals ofUrmia from September 2004 to September 2007 were assessed for HTLV-I infection antibodies.Results: In our 3 years study, 11 cases were diagnosed as Human T Lymphotropic Virus type I AssociatedMyelopathy/Tropical Spastic Paraparesis (HAM/TSP, 2 males and 9 females).The mean age of patients at thetime of diagnosis was 45.8 years. Dorsal and cervical MRI of all patients was normal. Serum Enzyme-LinkedImmuno-Sorbent Assay (ELISA) and Western blot (WB) for anti HTLV-I antibody in all patients was positive. Fourpatients underwent for lumbar puncture in which were normal in respect of cells and biochemistry, but positive foranti-HLTLV-I antibodies.Conclusion: HAM/TSP detection in West Azarbaijan in spite of its long distance from Khorasan Province showsthe importance of anti-HTLV-I Ab assay in the blood and CSF of every spastic paraparetic patient all over thecountry.
URI: http://koha.mediu.edu.my:8181/jspui/handle/123456789/4717
Other Identifiers: www.ircmj.com
http://www.doaj.org/doaj?func=openurl&genre=article&issn=15614395&date=2011&volume=13&issue=6&spage=428
Appears in Collections:Health Sciences

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.