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dc.creatorKnežević-Pogančev Marija-
dc.date2011-
dc.date.accessioned2013-05-30T11:59:14Z-
dc.date.available2013-05-30T11:59:14Z-
dc.date.issued2013-05-30-
dc.identifierhttp://www.doiserbia.nb.rs/img/doi/0025-8105/2011/0025-81051106295K.pdf-
dc.identifierhttp://www.doaj.org/doaj?func=openurl&genre=article&issn=00258105&date=2011&volume=64&issue=5-6&spage=295-
dc.identifier.urihttp://koha.mediu.edu.my:8181/jspui/handle/123456789/4934-
dc.descriptionIntroduction. Juvenile myasthenia is a chronic autoimmune neuromuscular disease characterized by varying degrees of fluctuating, painless muscle weakness and rapid fatigue of any muscles under voluntary control. Juvenile myasthenia is a form of myasthenia appearing in adolescent age, representing 10% to 15% of all cases of myasthenia gravis. Juvenile myasthenia is presented by a defect in the transmission of nerve impulses to muscles, resulting from a breakdown in the normal communication between nerves and muscles. In myasthenia, antibodies produced by the body’s own immune system block, alter, or destroy the receptors for acetylcholine. Juvenile myasthenia is neither directly inherited nor is it contagious. Signs and Symptoms. The first noticeable symptoms may be eye muscle weakness, difficulty in swallowing, or slurred speech. Juvenile myasthenia usually affects muscles innervated by the cranial nerves (face, lips, tongue, neck and throat), but it can affect any muscle group. Symptoms vary in type and severity with typical periods of exacerbation interspersed with periods of remission. When the muscles necessary for breathing are affected, a patient is said to be in a myasthenic crisis, which is a life-threatening situation. Disease Outcome and Treatment. Juvenile myasthenia produces sporadic but progressive weakness and abnormal fatigability of striated (skeletal) muscles, exacerbated by exercise and repeated movement, but improved by rest and anticholinesterase drugs. Juvenile myasthenia follows an unpredictable course of recurring exacerbations and periodic remissions. With current therapies, however, most cases of juvenile myasthenia are not as serious as the name implies. Although there is no known cure, drug treatment has improved prognosis and allows patients to lead relatively normal lives, except during exacerbations.-
dc.publisherDruštvo lekara Vojvodine Srpskog lekarskog društva-
dc.sourceMedicinski Pregled-
dc.subjectMyasthenia Gravis-
dc.subjectAdolescent-
dc.subjectAcetylcholine-
dc.subjectReceptors-
dc.subjectCholinergic + immunology-
dc.subjectSigns and Symptoms-
dc.subjectCholinesterase Inhibitors-
dc.subjectDisease Progression-
dc.subjectRecurrence-
dc.titleJuvenile myasthenia-
Appears in Collections:Health Sciences

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