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Please use this identifier to cite or link to this item: http://dspace.mediu.edu.my:8181/xmlui/handle/123456789/5701
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dc.creatorM.C. Sharma, S. Sharma*, A.D. Sharma-
dc.date2011-
dc.date.accessioned2013-05-30T13:18:14Z-
dc.date.available2013-05-30T13:18:14Z-
dc.date.issued2013-05-30-
dc.identifierhttp://ditonline.info/article/view/8119/4145-
dc.identifierhttp://www.doaj.org/doaj?func=openurl&genre=article&issn=09757619&date=2011&volume=3&issue=6&spage=100-
dc.identifier.urihttp://koha.mediu.edu.my:8181/jspui/handle/123456789/5701-
dc.descriptionA RP-HPLC method was developed and validated for quantitative determination of Atenolol and Hydrochlorothiazide in pharmaceutical dosage forms. The chromatography was carried out on a 25 cm × 4.6 mm i.d, 5-μm particle, Phenomenex Luna C18 column under reversed-phase partition chromatographic conditions. The mobile phase was a mixture of ammonium acetate (0.02M, pH 4.0 adjusted with glacial acetic acid) and acetonitrile in ratio of 40:60 (v/v) at a flow rate of 1.0ml/min. Clarithromycin was used as an internal standard. The linearity was established in the range of 20 - 400 ng/ml Atenolol and 5-150 ng/ml Hydrochlorothiazide for HPLC. This validated method can be used for estimation of Atenolol and Hydrochlorothiazide in pharmaceutical suspension.-
dc.publisherAssociation of Pharmaceutical Innovators-
dc.sourceDrug Invention Today-
dc.subjectAtenolol-
dc.subjectHydrochlorothiazide-
dc.subjectRP-HPLC-
dc.subjectAnalytical method validation-
dc.titleApplication to Dissolution Assessments; A Facile and Rapid procedure of Atenolol and Hydrochlorothiazide in Pharmaceutical Formulation by RP-HPLC assay Method-
Appears in Collections:Health Sciences

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