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http://dspace.mediu.edu.my:8181/xmlui/handle/123456789/5705| Title: | Simultaneous Determination and validation of Ziprasidone Hydrochloride in Dosage form by Densitometric |
| Keywords: | Ziprasidone hydrochloride HPTLC Validation |
| Issue Date: | 30-May-2013 |
| Publisher: | Association of Pharmaceutical Innovators |
| Description: | A simple, rapid and accurate High-performance thin-layer chromatography method has been established and validated for the simultaneous determination of Ziprasidone Hydrochloride in tablets. The method is based on HPTLC separation of the drugs followed by densitometric measurements of their spots at 277 nm. The separation was carried out on Merck TLC aluminium sheets of silica gel 60F-254 using mobile phase consisting of benzene: ethyl acetate: methanol: glacial acetic acid (4.0: 1.0:0.5:0.1 v/v/v/v). Calibration curves were linear in range of 1.625- 14.625 μg/spot and 0.1 - 0.9 μg/spot for Ziprasidone Hydrochloride. |
| URI: | http://koha.mediu.edu.my:8181/jspui/handle/123456789/5705 |
| Other Identifiers: | http://ditonline.info/article/view/8120/4146 http://www.doaj.org/doaj?func=openurl&genre=article&issn=09757619&date=2011&volume=3&issue=6&spage=102 |
| Appears in Collections: | Health Sciences |
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