Please use this identifier to cite or link to this item: http://dspace.mediu.edu.my:8181/xmlui/handle/1721.1/6789
Title: Synthesizing Regularity Exposing Attributes in Large Protein Databases
Keywords: representation reformulation
secondary structuresprediction
genetic algorithms
neural networks
clustering algorithm
sdecision tree systems
Issue Date: 9-Oct-2013
Description: This thesis describes a system that synthesizes regularity exposing attributes from large protein databases. After processing primary and secondary structure data, this system discovers an amino acid representation that captures what are thought to be the three most important amino acid characteristics (size, charge, and hydrophobicity) for tertiary structure prediction. A neural network trained using this 16 bit representation achieves a performance accuracy on the secondary structure prediction problem that is comparable to the one achieved by a neural network trained using the standard 24 bit amino acid representation. In addition, the thesis describes bounds on secondary structure prediction accuracy, derived using an optimal learning algorithm and the probably approximately correct (PAC) model.
URI: http://koha.mediu.edu.my:8181/xmlui/handle/1721
Other Identifiers: AITR-1444
http://hdl.handle.net/1721.1/6789
Appears in Collections:MIT Items

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