المستودع الأكاديمي جامعة المدينة

Malignant tumours of the minor salivary glands: a survival analysis of 17 years from a tertiary referral cancer centre.

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dc.creator Pandey M
dc.creator Thomas S
dc.creator Mathew A
dc.creator Nair M
dc.date 2003
dc.date.accessioned 2013-05-30T11:10:13Z
dc.date.available 2013-05-30T11:10:13Z
dc.date.issued 2013-05-30
dc.identifier http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2003;volume=49;issue=1;spage=25;epage=8;aulast=Pandey
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=00223859&date=2003&volume=49&issue=1&spage=25
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/4404
dc.description BACKGROUND: Malignant tumours of the minor salivary glands are rare and constitute less than 0.5% of all malignant neoplasms. AIM: This study was carried out to evaluate the clinical presentation, site distribution, treatment, survival and predictors of survival in malignant minor salivary gland tumours. SETTING: A tertiary care, superspeciality referral hospital. DESIGN: Retrospective analysis. PATIENTS AND METHOD: Forty-two cases of minor salivary gland tumours treated over a period of 17 years were reviewed for clinical presentation, histopathology, stage distribution, treatment and treatment outcome. STATISTICAL ANALYSIS: Survival by Kaplan Meier Method and the outcomes were compared using log-rank test. RESULTS: The mean age of the patients was 46.9 years with a male to female ratio of 1.4:1. Majority of the patients presented with a painless progressive swelling, with 13 (31%) of them in T2 stage. About one-third of the patients had palpable lymph nodes at presentation, while none had distant metastasis. Palate was the commonest site and mucoepidermoid carcinoma was the commonest hispathological type. About 1/3 of the patients were treated with primary surgery and were followed up by adjuvant radiotherapy. Seven patients underwent palliative treatment alone. Over a mean follow-up of 30 months, 5 patients failed. The disease free survival was 72% at 5-year, none of the factors studied were found to significantly influence survival. CONCLUSIONS: Results of the present study suggest that minor salivary gland tumours should be treated with primary surgery irrespective of site and histological type to achieve best loco-regional control and survival.
dc.publisher Medknow Publications
dc.source Journal of Postgraduate Medicine
dc.subject Adolescent
dc.subject Adult
dc.subject Aged
dc.subject Carcinoma
dc.subject diagnosis
dc.subject pathology
dc.subject therapy
dc.subject Disease-Free Survival
dc.subject Female
dc.subject Human
dc.subject Male
dc.subject Middle Age
dc.subject Neoplasm Staging
dc.subject Palate
dc.subject pathology
dc.subject Retrospective Studies
dc.subject Salivary Gland Neoplasms
dc.subject diagnosis
dc.subject pathology
dc.subject therapy
dc.subject Survival Analysis
dc.subject Treatment Outcome
dc.title Malignant tumours of the minor salivary glands: a survival analysis of 17 years from a tertiary referral cancer centre.


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