The purpose of this study was to evaluate the effect of anabolic steroids consumption on Creactiveprotein (CRP) in bodybuilders. Sixty healthy men in three groups include First group(FG) were bodybuilders which had consumed anabolic steroids (n=20); second group (SG) wasbodybuilders which hadn’t consumed anabolic steroids (n=20) and third group (TG) wereuntrained subjects as control (n=20) participate in the study. CRP concentration; Strength andvolume of the forearm; pectoral major and femur muscles were measured. Strength and CRPwere greater in FG compared to other groups (P<0/05). But differences between SG and TGwere not significant. Forearm and femur circumstance were grater in FG than other groups.Furthermore; this was grater in SG than TG. However; chest circumstance was grater in FG andSG than TG only. There were no significant differences in speed between groups. Anabolicsteroid consumption for muscle strength and volume improvement in bodybuilders accompanywith higher level of CRP (as a cardiovascular risk factor).