| dc.creator |
Ren, L. |
|
| dc.creator |
Chow, Gan-Moog |
|
| dc.date |
2003-12-08T15:31:48Z |
|
| dc.date |
2003-12-08T15:31:48Z |
|
| dc.date |
2003-01 |
|
| dc.date.accessioned |
2013-10-09T02:32:28Z |
|
| dc.date.available |
2013-10-09T02:32:28Z |
|
| dc.date.issued |
2013-10-09 |
|
| dc.identifier |
http://hdl.handle.net/1721.1/3787 |
|
| dc.identifier.uri |
http://koha.mediu.edu.my:8181/xmlui/handle/1721 |
|
| dc.description |
Near IR (NIR) sensitive Au-Au₂S nanoparticles were prepared by mixing HAuCl₄ and Na₂S in aqueous solutions. An anti-tumor drug, cis-platin, was adsorbed onto Au-Au₂S nanoparticle surface via the 11-mercaptoundecanoic acid layers. The results showed that the degree of adsorption of cis-platin onto Au-Au₂S nanoparticles was controlled by the pH value of solution, and the drug release was sensitive to NIR irradiation. The cis-platin loaded Au-Au₂S nanoparticles can be potentially applied as NIR activated drug delivery carrier. |
|
| dc.description |
Singapore-MIT Alliance (SMA) |
|
| dc.format |
101640 bytes |
|
| dc.format |
application/pdf |
|
| dc.language |
en_US |
|
| dc.relation |
Molecular Engineering of Biological and Chemical Systems (MEBCS); |
|
| dc.subject |
drug delivery |
|
| dc.subject |
near-infrared |
|
| dc.subject |
Au-Au2 |
|
| dc.subject |
nanoparticles |
|
| dc.subject |
cis-Platin |
|
| dc.title |
NIR-Sensitive Au-Au₂S Nanoparticles for Drug Delivery |
|
| dc.type |
Article |
|